Intereses y/o líneas de investigación
Química de los alimentos: Extracción y caracterización de compuestos bioactivos desde matrices
alimentarias y subproductos agroindustriales.
Publicaciones y patentes
- Salgado, P., Contreras, D., Mansilla, H. D., Márquez, K., Vidal, G., Cobos, C. J., & Mártire, D. O. (2017). Experimental and computational investigation of the substituent effects on the reduction of Fe3+ by 1,2-dihydroxybenzenes. New J. Chem., 41(21), 12685-12693. https://doi.org/10.1039/C7NJ01322A
- Tarifeño-Saldivia, E., Aguilar, A., Contreras, D., Mercado, L., Morales-Lange, B., Márquez, K., Henríquez, A., Riquelme-Vidal, C., & Boltana, S. (2018). Iron Overload Is Associated With Oxidative Stress and Nutritional Immunity During Viral Infection in Fish. Frontiers in Immunology, 9, 1296. https://doi.org/10.3389/fimmu.2018.01296
- Márquez, K., Contreras, D., Salgado, P., & Mardones, C. (2019). Production of hydroxyl radicals and their relationship with phenolic compounds in white wines. Food Chemistry, 271, 80-86. https://doi.org/10.1016/j.foodchem.2018.07.165
- Salgado, P., Márquez, K., Rubilar, O., Contreras, D., & Vidal, G. (2019). The effect of phenolic compounds on the green synthesis of iron nanoparticles (FexOy-NPs) with photocatalytic activity. Applied Nanoscience, 9(3), 371-385. https://doi.org/10.1007/s13204-018-0931-5
- Contreras, D., Melin, V., Márquez, K., Pérez-González, G., Mansilla, H. D., Pecchi, G., & Henríquez, A. (2019). Selective oxidation of cyclohexane to cyclohexanol by BiOI under visible light: Role of the ratio (1 1 0)/(0 0 1) facet. Applied Catalysis B: Environmental, 251, 17-24. https://doi.org/10.1016/j.apcatb.2019.03.058
- Márquez, K., Pérez-Navarro, J., Hermosín-Gutiérrez, I., Gómez-Alonso, S., Mena-Morales, A., García-Romero, E., & Contreras, D. (2019). Systematic study of hydroxyl radical production in white wines as a function of chemical composition. Food Chemistry, 288, 377-385. https://doi.org/10.1016/j.foodchem.2019.03.005
- Mieres-Castro, D., Schmeda-Hirschmann, G., Theoduloz, C., Gómez-Alonso, S., Pérez-Navarro, J., Márquez, K., & Jiménez-Aspee, F. (2019a). Antioxidant activity and the isolation of polyphenols and new iridoids from Chilean Gaultheria phillyreifolia and poeppigii berries. Food Chemistry, 291, 167-179. https://doi.org/10.1016/j.foodchem.2019.04.019
- Pino Ramos, L. L., Jiménez-Aspee, F., Theoduloz, C., Burgos-Edwards, A., Domínguez-Perles, R., Oger, C., Durand, T., Gil-Izquierdo, Á., Bustamante, L., Mardones, C., Márquez, K., Contreras, D., & Schmeda-Hirschmann, G. (2019). Phenolic, oxylipin and fatty acid profiles of the Chilean hazelnut (Gevuina avellana): Antioxidant activity and inhibition of pro-inflammatory and metabolic syndrome-associated enzymes. Food Chemistry, 298, 125026. https://doi.org/10.1016/j.foodchem.2019.125026
- Barra, P., Márquez, K., Gil-Castell, Ó., Mujica, J., Amparo, R., & Faccini, M. (2019). Spray-Drying Performance and Thermal Stability of L-Ascorbic Acid Microencapsulated with Sodium Alginate and Gum Arabic. Molecules, 24. https://doi.org/10.3390/molecules24162872
- Mieres-Castro, D., Schmeda-Hirschmann, G., Theoduloz, C., Gómez-Alonso, S., Pérez-Navarro, J., Márquez, K., & Jiménez-Aspee, F. (2019b). Chilean “chaura” berries (Gaultheria phillyreifolia and poeppigii): Isolation of secondary metabolites and antioxidant activity. Planta Medica, 85(18), P-147. https://doi.org/10.1055/s-0039-3399871
- Marchante, L., Marquez, K., Contreras, D., Izquierdo-Cañas, P. M., García-Romero, E., & Díaz-Maroto, M. C. (2020). Potential of Different Natural Antioxidant Substances to Inhibit the 1-Hydroxyethyl Radical in SO2-Free Wines. Journal of Agricultural and Food Chemistry, 68(6), 1707-1713. https://doi.org/10.1021/acs.jafc.9b07024
- Marchante, L., Márquez, K., Contreras, D., Izquierdo‐Cañas, P. M., García‐Romero, E., & Díaz‐Maroto, M. C. (2020). Impact of oenological antioxidant substances on the formation of 1‐hydroxyethyl radical and phenolic composition in SO2 free red wines. Journal of the Science of Food and Agriculture, 100(8), 3401-3407. https://doi.org/10.1002/jsfa.10374
- Romero, R., Márquez, K., Benítez, F. J., Toro-Labbé, A., Cornejo-Ponce, L., Melín, V., & Contreras, D. (2022). Chemiluminescence emission in Fenton reaction driven by 1,2-dihydroxybenzenes: Mechanistic approaches using 4-substituted ligands. Journal of Photochemistry and Photobiology A: Chemistry, 426, 113744. https://doi.org/10.1016/j.jphotochem.2021.113744
- Márquez, K., Márquez, N., Ávila, F., Cruz, N., Burgos-Edwards, A., Pardo, X., & Carrasco, B. (2022). Oleuropein-Enriched Extract From Olive Mill Leaves by Homogenizer-Assisted Extraction and Its Antioxidant and Antiglycating Activities. Frontiers in Nutrition, 9, 895070. https://doi.org/10.3389/fnut.2022.895070
- Ávila, F., Cruz, N., Alarcon-Espósito, J., Nina, N., Paillan, H., Márquez, K., Fuentealba, D., Burgos-Edwards, A., Theoduloz, C., Vejar-Vivar, C., & Schmeda-Hirschmann, G. (2022). Inhibition of advanced glycation end products and protein oxidation by leaf extracts and phenolics from Chilean bean landraces. Journal of Functional Foods, 98, 105270. https://doi.org/10.1016/j.jff.2022.105270
- Márquez, K., Jiménez-Aspee, F., Márquez, N., Salgado, P., & Contreras, D. (2023). Use of NIR spectroscopy and multivariate regression for prediction of pentosan content in wood pulp. European Journal of Wood and Wood Products, 81(2), 547-555. https://doi.org/10.1007/s00107-022-01896-2
- Burgos-Edwards, A., Theoduloz, C., Márquez, K., Carrasco, B., & Schmeda-Hirschmann, G. (2023). Leaf development in Chilean bean landraces (Phaseolus vulgaris) affects phenolic composition and α-glucosidase inhibition. Scientia Horticulturae, 309, 111613. https://doi.org/10.1016/j.scienta.2022.111613
- Nina, N., Theoduloz, C., Paillán, H., Jiménez-Aspee, F., Márquez, K., Schuster, K., Becker, L., Oellig, C., Frank, J., & Schmeda-Hirschmann, G. (2023). Chemical profile and bioactivity of Chilean bean landraces (Phaseolus vulgaris L.). Journal of Functional Foods, 104, 105513. https://doi.org/10.1016/j.jff.2023.105513
- Nina, N., Theoduloz, C., Tapia, G., Jimenéz-Aspee, F., Márquez, K., & Schmeda-Hirschmann, G. (2023). Changes in polyphenol composition, antioxidant capacity and enzyme inhibition in Phaseolus vulgaris L. submitted to hydric stress. Scientia Horticulturae, 317, 112070. https://doi.org/10.1016/j.scienta.2023.112070
- Antileo-Laurie, J., Theoduloz, C., Burgos-Edwards, A., Jiménez-Aspee, F., Márquez, K., Fischer, M., & Schmeda-Hirschmann, G. (2023). Antioxidant capacity and inhibition of metabolic syndrome-associated enzymes by Cryptocarya alba fruits. Food Research International, 173, 113343. https://doi.org/10.1016/j.foodres.2023.113343
- Manuela de Almeida Samary da Silva, Raquel Bridi, María Fernanda Arias-Santé, Miguel Angel Rincón-Cervera, Lee A. Meisel, Samantha Ottani Rhein, c, Omar Porras, Katherine Márquez Calvo, Basílio Carrasco, Adriano Costa de Camargo (2024). Soluble and insoluble-bound phenolic bioactive compounds of Tortola bean leaf and their antioxidant properties in chemical-based assays and Caco-2 cells. Food Bioscience, 57, 103616. https://doi.org/10.1016/j.fbio.2024.103616
- K Márquez, O Arriagada, R Pérez-Díaz, RA Cabeza, A Plaza, B Arévalo, LA Meisel, D Ojeda, …, B Carrasco (2024). Nutritional Characterization of Chilean Landraces of Common Bean. Plants, 13(6), 817. https://doi.org/10.3390/plants13060817
- Osvin Arriagada, Bárbara Arévalo, Igor Pacheco, Andrés R. Schwember, Lee A. Meisel, Herman Silva, Katherine Márquez, …, Basilio Carrasco (2024). A Past Genetic Bottleneck from Argentine Beans and a Selective Sweep Led to the Race Chile of the Common Bean (Phaseolus vulgaris L.). International Journal of Molecular Sciences, 25, 4081. https://doi.org/10.3390/ijms25074081
- Salgado, P., Rubilar, O., Salazar, C., Márquez, K., Vidal, G (2024). In Situ Synthesis of Cu2O Nanoparticles Using Eucalyptus globulus Extract to Remove a Dye via Advanced Oxidation. Nanomaterials, 14(13), 1087. https://doi.org/10.3390/nano14131087
- Pablo Salgado, Katherine Márquez, Gladys Vidal (2024). Biogenic Synthesis Based on Cuprous Oxide Nanoparticles Using Eucalyptus globulus Extracts and Its Effectiveness for Removal of Recalcitrant Compounds. Catalysts, 14, 525. https://doi.org/10.3390/catal14080525
- Pia Eckhof, Katherine Márquez, Johanita Kruger, Nélida Nina, Elizabeth Ramirez-Jara, Jan Frank, Felipe Jimenez Aspee (2024). Bioaccessibility of carotenoids, tocochromanols, and iron from common bean (Phaseolus vulgaris L.) landraces. Food Research International, 194, 114935. https://doi.org/10.1016/j.foodres.2024.114935
- Nadia Cruz, Katherine Márquez, Nélida Nina, Aracely-Basoalto-Cubillos, Alejandro Vallejos-Almirall, Francisco Armijo, Guillermo Schmeda-Hirschmann, and Felipe Ávila (2025). Thermal treatment under oxidative conditions increases the antioxidant and antiglycation activity of Chilean Tórtola beans (Phaseolus vulgaris). Food Chemistry, 463, 141085. https://doi.org/10.1016/j.foodchem.2024.141085
- Felipe Ávila, Natalia Martínez, Nicolás Mora, Katherine Márquez, and Felipe Jiménez-Aspee (2025). Effect of thermal treatment on the extraction, antioxidant, and antiglycation activities of (poly)phenols from Ribes magellanicum. Molecules, 30(2), 318. https://doi.org/10.3390/molecules30020318
- Katherine Márquez, Felipe Leyton-Soto, Camila Labra, Catalina Carrasco, Minke Tang, Guillermo Schmeda-Hirschmann (2025). Chemical Composition and Lipids from “Tofu” of Chilean Phaseolus vulgaris. Plant Foods for Human Nutrition, 80:156. https://doi.org/10.1007/s11130-025-01391-y
Proyectos
- “Mejoramiento del rendimiento, poder espesante y viscosidad del agar proveniente del alga Gracilaria Chilensis, mediante nuevas aplicaciones tecnológicas y optimización del proceso de extracción”. FONDEF ID15I10069. Cargo: Personal técnico. 2017.
- “Desarrollo de un nuevo bioproceso de acumulación de astaxantina vía inducción no autotrófica en Haematococcus lacustri para la industria nutraceútica”. FONDEF ID18I10259. Cargo: Investigadora. 2018.
- “Materiales nanoestructurados para dar soluciones al sector acuicultura y alimentación”. Nano-Microencapsulación de pigmentos naturales y antioxidantes para el área acuícola y alimentación”. Corfo “CENTRO DE EXCELENCIA EN NANOTECNOLOGÍA”. Cargo: Investigadora. 2019 – 2020.
- “Ω-Cheese: Microencapsulación de aceite de semillas de cáñamo, rico en ácidos grasos ω-3 y ω-6, para su incorporación en una nueva línea de quesos”. Corfo 17CONTEC-83626. Cargo: Investigadora. 2019 – 2020.
- “Obtención de hidroxitirosol a partir de la valorización de hojas de poda provenientes de olivos”. Proyecto privado para empresa Olivos del Sur. Cargo: Investigadora. 2019 – 2020.
- “Fortalecimiento para la continuidad del Centro de Estudios en Alimentos Procesados, CEAP”. ANID R19A10001. Cargo: Investigadora. 2019 – 2022.
- Fortalecimiento de Centros Regionales “Multidisciplinary studies on bioactive compounds from the Chilean Phaseolus vulgaris L. landraces and their potential efecto in the prevention of non-communicable chronic diseases”. ANID R20F0001 Cargo: Investigadora. 2021 – 2025.
- FIC Regional Maule BIP 40.036.329-0 “Compuestos bioactivos de extractos naturales de la región del Maule para el desarrollo de nutracéuticos en la prevención y tratamiento de la enfermedad de Alzheimer”. Cargo: Investigador Responsable. 2022 – 2024.
- “Formulación de productos de panificación suplementados con harina de porotos nativos chilenos para disminuir respuestas glicémicas postprandiales y agregación plaquetaria en personas mayores: Un estudio piloto”. Centro Interuniversitario de Envejecimiento Saludable (CIES 002). Cargo: Investigador Colaborador.2022 – 2024.
- “Desarrollo de un potencial ingrediente funcional a partir de legumbres fermentadas para el desarrollo de alimentos saludables”. FIC Regional Maule BIP 40.047.043-0. Cargo: Directora. 2023 – 2025.
- “Potential antiglycating effect and antioxidant activity of bioactive peptides of the protein hydrolysate from common beans (Phaseolus vulgaris L.) genotypes race Chile”. Fondecyt Iniciación Cod. 11231166. Cargo: Investigador Responsable. 2023 – 2025.